A variety of popular exchanges like Binance, Crypto.com, Kucoin and more support direct withdraws from OP Mainnet.
If the centralized exchange supports OP Mainnet then you will be able to transfer directly from OP Mainnet to the respective exchange. If your favorite exchange does not support OP Mainnet yet, then you have to bridge your assets into a network they do support, such as the Ethereum mainnet.